ALI, ARDS & Ventilator Research
Acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome (ARDS), typically develop following an acute systemic (e.g. sepsis) or lung (e.g. pneumonia, aspiration, trauma) injury. These serious and life threatening conditions are characterized by a wide-spread lung inflammation, alveolar and capillary damage and dysfunction, as well as a long term build-up of scar tissue. From a lung function perspective, these lead to pulmonary edema formation, collapse of lung areas, poor blood oxygenation, and enhanced breathing efforts.